Title : SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation.

Pub. Date : 2021 Apr 23

PMID : 33890572






1 Functional Relationships(s)
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1 Together with quantitative cell biology approaches, the screen reveals an essential role for biophysical aspects of the membrane, particularly cholesterol-rich regions, in spike-mediated fusion, which extends to replication-competent SARS-CoV-2 isolates. Cholesterol surface glycoprotein Severe acute respiratory syndrome coronavirus 2