Title : Decursin alleviates the aggravation of osteoarthritis via inhibiting PI3K-Akt and NF-kB signal pathway.

Pub. Date : 2021 Aug

PMID : 33878544






2 Functional Relationships(s)
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1 In vitro cell experiments, the inflammatory response in chondrocytes is mediated via interleukin-1beta (IL-1beta), which led to abnormal secretion of pro-inflammatory factors, such as prostaglandin E2 (PGE2), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-alpha), cyclooxygenase-2 (COX-2), nitric oxide (NO) and inducible nitric oxide synthase (iNOS). Dinoprostone interleukin 1 beta Mus musculus
2 In vitro cell experiments, the inflammatory response in chondrocytes is mediated via interleukin-1beta (IL-1beta), which led to abnormal secretion of pro-inflammatory factors, such as prostaglandin E2 (PGE2), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-alpha), cyclooxygenase-2 (COX-2), nitric oxide (NO) and inducible nitric oxide synthase (iNOS). Dinoprostone interleukin 1 beta Mus musculus