Title : Effects of a combined therapy of bortezomib and ionizing radiation on chondrosarcoma three-dimensional spheroid cultures.

Pub. Date : 2021 Jun

PMID : 33868466






1 Functional Relationships(s)
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1 Both cell types exhibited a slight decrease in viability following increasing doses of IR; the chondrosarcoma cells demonstrated a significant dose-dependent increase in the expression levels of the DNA damage marker histone H2AX phosphorylation at serine 139 (gammaH2AX). Serine H2A.X variant histone Homo sapiens