Title : Disulfiram/copper shows potent cytotoxic effects on myelodysplastic syndromes via inducing Bip-mediated apoptosis and suppressing autophagy.

Pub. Date : 2021 Jul 5

PMID : 33865831






2 Functional Relationships(s)
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1 Disulfiram/copper shows potent cytotoxic effects on myelodysplastic syndromes via inducing Bip-mediated apoptosis and suppressing autophagy. Disulfiram heat shock protein family A (Hsp70) member 5 Homo sapiens
2 Mechanistically, the anti-MDS effectiveness of DSF/Cu was potentially associated with activation of the ER stress-related Bip pathway and inactivation of the Akt pathway. Disulfiram heat shock protein family A (Hsp70) member 5 Homo sapiens