Title : Quercetin inhibits histamine-induced calcium influx in human keratinocyte via histamine H4 receptors.

Pub. Date : 2021 Jul

PMID : 33862555






2 Functional Relationships(s)
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1 Activation of histamine receptors and calcium influx via TRPV1 could be related to histamine-induced itch and skin inflammation. Calcium transient receptor potential cation channel subfamily V member 1 Homo sapiens
2 These data suggest that quercetin could decrease histamine 4 receptor-induced calcium influx through the TRPV1 channel and could provide a molecular mechanism of quercetin in anti-itching, anti-inflammatory, and unpleasant sensations. Calcium transient receptor potential cation channel subfamily V member 1 Homo sapiens