Title : Interaction of a Triantennary Quinoline Glycoconjugate with the Asialoglycoprotein Receptor.

Pub. Date : 2021 Jul 20

PMID : 33860988






1 Functional Relationships(s)
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1 A novel triantennary galactose conjugated quinoline derivative 4 has been synthesized that demonstrates a 17 fold higher binding affinity to isolated ASGPR-H1-CRD protein receptor (K d ~ 54 microM) in comparison to D-Galactose (Kd ~ 900 microM). Galactose asialoglycoprotein receptor 1 Homo sapiens