Title : Complement C5a promotes antigen cross-presentation by Peyer's patch monocyte-derived dendritic cells and drives a protective CD8+ T cell response.

Pub. Date : 2021 Apr 13

PMID : 33852847






1 Functional Relationships(s)
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1 Stimulation of C5aR+ LysoDCs by C5a increases reactive oxygen species levels, leading to efficient antigen cross-presentation, which elicits an antigen-specific CD8+ T cell response. Reactive Oxygen Species hemolytic complement Mus musculus