Title : MicroRNA-34a regulates 5-HT2C expression in dorsal raphe and contributes to the anti-depressant-like effect of fluoxetine.

Pub. Date : 2021 Jun 1

PMID : 33845072






2 Functional Relationships(s)
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1 In this study, acute and chronic fluoxetine treatment differentially alters the expression of 5-HT2C and microRNA-34a in the dorsal raphe. Fluoxetine 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus
2 Our results demonstrate a new miR-34a-mediated regulatory mechanism of 5-HT2C expression in the dorsal raphe and implicate it in eliciting the behavioral responses to chronic fluoxetine treatment. Fluoxetine 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus