Pub. Date : 2021 Sep
PMID : 33834359
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, we confirm of therapeutic effects of GB1107, a cell-penetrating galectin-3 specific inhibitor, using orthotopic gastric cancer-bearing mice RESULTS: Increased levels of galectin-3 and STAT3 phosphorylation were detected in the stomach tissues of WNT1-overexpressing mouse models. | GB1107 | signal transducer and activator of transcription 3 | Mus musculus |
| 2 | GB1107, a specific membrane-penetrating inhibitor of galectin-3, significantly reduced the activation of both STAT3 and beta-catenin and inhibited tumor growth in orthotopic gastric cancer-bearing mice. | GB1107 | signal transducer and activator of transcription 3 | Mus musculus |