Title : The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma.

Pub. Date : 2021 Apr 8

PMID : 33830080






1 Functional Relationships(s)
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1 Cotargeting of aberrant p16-CDK4/6-RB signaling and CRTC1-MAML2 fusion-activated AREG/EGFR signaling with the respective CDK4/6 inhibitor Palbociclib and EGFR inhibitor Erlotinib produced enhanced antitumor responses in vitro and in vivo. Erlotinib Hydrochloride amphiregulin Homo sapiens