Title : Dexmedetomidine ameliorates lipopolysaccharide-induced acute lung injury by inhibiting the PI3K/Akt/FoxO1 signaling pathway.

Pub. Date : 2021 Jun

PMID : 33821300






1 Functional Relationships(s)
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1 RESULTS: DEX significantly inhibited LPS-induced increases in the lung weight/body weight ratio and lung wet/dry weight ratio, decreased inflammatory cell infiltration, and decreased the production of proinflammatory factors, such as interleukin-1beta (IL-1beta), IL-6, and tumor necrosis factor alpha (TNF-alpha)in the lungs. Dexmedetomidine interleukin 1 beta Mus musculus