Pub. Date : 2020
PMID : 33817278
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | miR-339-3p regulated acute pancreatitis induced by caerulein through targeting TNF receptor-associated factor 3 in AR42J cells. | Ceruletide | Tnf receptor-associated factor 3 | Rattus norvegicus |
| 2 | Meanwhile, caerulein also reduced the expression of miR-339-3p and induced the expression of TRAF3 in rat pancreatic acinar cells. | Ceruletide | Tnf receptor-associated factor 3 | Rattus norvegicus |
| 3 | In addition, the suppression effects of miR-339-3p on cell inflammation and apoptosis in caerulein-induced AP were reversed by enhancing TRAF3 expression. | Ceruletide | Tnf receptor-associated factor 3 | Rattus norvegicus |
| 4 | Overexpression of miR-339-3p inhibited cell inflammation and cell apoptosis in caerulein-induced AP through modulating TRAF3 expression via the p38 pathway, providing a new therapeutic target in the treatment of AP. | Ceruletide | Tnf receptor-associated factor 3 | Rattus norvegicus |