Title : Reversine and herbal Xiang-Sha-Liu-Jun-Zi decoction ameliorate thioacetamide-induced hepatic injury by regulating the RelA/NF-κB/caspase signaling pathway.

Pub. Date : 2020

PMID : 33817258






1 Functional Relationships(s)
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1 Reversine also modulated the mRNA levels of inflammatory cytokines, such as RelA, interleukin (IL)-17A, IL-22, IL-1beta, IL-6, NLR family pyrin domain containing 3, platelet-derived growth factor, and monocyte chemoattractant protein, and suppressed nuclear factor (NF)-kappaB (p65) phosphorylation and caspase 1 activation. 2-(4-morpholinoanilino)-6-cyclohexylaminopurine caspase 1 Rattus norvegicus