Pub. Date : 2021 Apr 20
PMID : 33784244
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Testosterone regulation on quiescin sulfhydryl oxidase 2 synthesis in the epididymis. | Testosterone | quiescin sulfhydryl oxidase 2 | Homo sapiens |
| 2 | In the present study, we extended our earlier findings on a promising epididymal protein, quiescin sulfhydryl oxidase 2 (QSOX2), and demonstrated a positive correlation between testosterone and QSOX2 protein synthesis through use of loss- and restore-of-function animal models. | Testosterone | quiescin sulfhydryl oxidase 2 | Homo sapiens |
| 3 | In the present study, we extended our earlier findings on a promising epididymal protein, quiescin sulfhydryl oxidase 2 (QSOX2), and demonstrated a positive correlation between testosterone and QSOX2 protein synthesis through use of loss- and restore-of-function animal models. | Testosterone | quiescin sulfhydryl oxidase 2 | Homo sapiens |
| 4 | Moreover, based on transcriptomic analyses and 2-dimensional culture system, we determined that an additional polarized effect of glutamate is indispensable for the regulatory action of testosterone on QSOX2 synthesis. | Testosterone | quiescin sulfhydryl oxidase 2 | Homo sapiens |
| 5 | In conclusion, we propose non-canonical testosterone signaling supports epididymal QSOX2 protein synthesis, providing a novel perspective on the regulation of sperm maturation within the epididymis. | Testosterone | quiescin sulfhydryl oxidase 2 | Homo sapiens |