Pub. Date : 2021 Oct
PMID : 33782967
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Transient receptor potential vanilloid 1 (TRPV1) channels are nonselective cation channels that permeate sodium and calcium. | Calcium | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 2 | Transient receptor potential vanilloid 1 (TRPV1) channels are nonselective cation channels that permeate sodium and calcium. | Calcium | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 3 | By electrophysiology and calcium imaging, pharmacological blocker of TRPV1 and the molecular tool TRPV1beta (which could functionally knockdown TRPV1) were found to decrease the rate and diastolic depolarization slope of spontaneous action potentials, and the amplitude and frequency of global calcium transients. | Calcium | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 4 | By electrophysiology and calcium imaging, pharmacological blocker of TRPV1 and the molecular tool TRPV1beta (which could functionally knockdown TRPV1) were found to decrease the rate and diastolic depolarization slope of spontaneous action potentials, and the amplitude and frequency of global calcium transients. | Calcium | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 5 | By electrophysiology and calcium imaging, pharmacological blocker of TRPV1 and the molecular tool TRPV1beta (which could functionally knockdown TRPV1) were found to decrease the rate and diastolic depolarization slope of spontaneous action potentials, and the amplitude and frequency of global calcium transients. | Calcium | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 6 | By electrophysiology and calcium imaging, pharmacological blocker of TRPV1 and the molecular tool TRPV1beta (which could functionally knockdown TRPV1) were found to decrease the rate and diastolic depolarization slope of spontaneous action potentials, and the amplitude and frequency of global calcium transients. | Calcium | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 7 | By calcium imaging, in the absence of external calcium, TRPV1-specific opener increased intracellular calcium; this increase was abolished by preincubation with caffeine, which could deplete SR calcium store. | Calcium | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 8 | The results suggest that TRPV1 controls calcium release from the SR. By electrophysiology, TRPV1 blockade and functional knockdown of TRPV1 decreased the Na+ /Ca2+ exchanger (NCX) currents from both the forward and reverse modes, suggesting that sodium and calcium through TRPV1 stimulate the NCX activity. | Calcium | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |
| 9 | The results suggest that TRPV1 controls calcium release from the SR. By electrophysiology, TRPV1 blockade and functional knockdown of TRPV1 decreased the Na+ /Ca2+ exchanger (NCX) currents from both the forward and reverse modes, suggesting that sodium and calcium through TRPV1 stimulate the NCX activity. | Calcium | transient receptor potential cation channel subfamily V member 1 | Homo sapiens |