Title : Multiple bioanalytical methods reveal a thyroid-disrupting mechanism related to the membrane receptor integrin αvβ3.

Pub. Date : 2021 Jun 15

PMID : 33773180






1 Functional Relationships(s)
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1 Moreover, DEHP activated the downstream extracellular regulated protein kinase (ERK1/2) pathway, upregulating the gene expression of raf-1, MEK-1 and MAPK1 and increasing the protein levels of p-ERK; interestingly, ERK1/2 activation and c-fos upregulation induced by DEHP were attenuated by PD98059 (an ERK1/2 inhibitor). 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one Eph receptor B1 Rattus norvegicus