Title : miR-26b enhances the sensitivity of hepatocellular carcinoma to Doxorubicin via USP9X-dependent degradation of p53 and regulation of autophagy.

Pub. Date : 2021

PMID : 33767588






2 Functional Relationships(s)
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1 miR-26b enhances the sensitivity of hepatocellular carcinoma to Doxorubicin via USP9X-dependent degradation of p53 and regulation of autophagy. Doxorubicin ubiquitin specific peptidase 9 X-linked Homo sapiens
2 Our current data indicate that miR-26b enhances HCC cell sensitivity to doxorubicin through diminishing USP9X-mediated p53 de-ubiquitination caused by DNA damaging drugs and autophagy regulation. Doxorubicin ubiquitin specific peptidase 9 X-linked Homo sapiens