Title : Synthesis and biological evaluation of disulfides as anticancer agents with thioredoxin inhibition.

Pub. Date : 2021 May

PMID : 33756234






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1 Synthesis and biological evaluation of disulfides as anticancer agents with thioredoxin inhibition. Disulfides thioredoxin Homo sapiens
2 Herein, we synthesized 72 disulfides and evaluated theirinhibition for Trx and antitumor activity. Disulfides thioredoxin Homo sapiens
3 Next, we performed kinetic studies of both two disulfides, 68 had faster inhibition of Trx than 69. Disulfides thioredoxin Homo sapiens