Title : Tight binding of cytochrome b5 to cytochrome P450 17A1 is a critical feature of stimulation of C21 steroid lyase activity and androgen synthesis.

Pub. Date : 2021 Jan-Jun

PMID : 33753170






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Tight binding of cytochrome b5 to cytochrome P450 17A1 is a critical feature of stimulation of C21 steroid lyase activity and androgen synthesis. Steroids TBL1X/Y related 1 Homo sapiens
2 The strongest stimulation of catalytic activity by b5 is in the P450 17A1 lyase reaction, an essential step in androgen synthesis from 21-carbon (C21) steroids, making this an excellent model system to interrogate b5 function. Steroids TBL1X/Y related 1 Homo sapiens