Title : Single-component, self-assembling, protein nanoparticles presenting the receptor binding domain and stabilized spike as SARS-CoV-2 vaccine candidates.

Pub. Date : 2021 Mar

PMID : 33741598






1 Functional Relationships(s)
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1 We then identified heptad repeat 2 (HR2) in S2 as the cause of spike metastability, designed an HR2-deleted glycine-capped spike (S2GDeltaHR2), and displayed S2GDeltaHR2 on SApNPs. Glycine surface glycoprotein Severe acute respiratory syndrome coronavirus 2