Pub. Date : 2021
PMID : 33738259
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hsp90 downregulation by shHsp90 or inhibitor BIIB021 increased the sensitivity of multi-drug resistant ovarian cancer cells to paclitaxel and cisplatin, and augmented the drugs-induced apoptosis. | Cisplatin | heat shock protein 90 alpha family class A member 1 | Homo sapiens |
| 2 | Furthermore, Hsp90 enhanced the AKT/GSK3beta signaling, and AKT signaling played a critical role in Hsp90-induced accumulation and transcriptional activity of beta-catenin, as well as multi-drug resistance to paclitaxel and cisplatin. | Cisplatin | heat shock protein 90 alpha family class A member 1 | Homo sapiens |
| 3 | Furthermore, Hsp90 enhanced the AKT/GSK3beta signaling, and AKT signaling played a critical role in Hsp90-induced accumulation and transcriptional activity of beta-catenin, as well as multi-drug resistance to paclitaxel and cisplatin. | Cisplatin | heat shock protein 90 alpha family class A member 1 | Homo sapiens |