Title : MicroRNA-874-3p promotes testosterone-induced granulosa cell apoptosis by suppressing HDAC1-mediated p53 deacetylation.

Pub. Date : 2021 Apr

PMID : 33732332






3 Functional Relationships(s)
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1 MicroRNA-874-3p promotes testosterone-induced granulosa cell apoptosis by suppressing HDAC1-mediated p53 deacetylation. Testosterone tumor protein p53 Homo sapiens
2 Furthermore, compared with the control group, testosterone treatment notably increased p53 expression and acetylation. Testosterone tumor protein p53 Homo sapiens
3 Collectively, the results of the present study indicated that miR-874-3p was upregulated in PCOS and promoted testosterone-induced GC apoptosis by suppressing HDAC1-mediated p53 deacetylation. Testosterone tumor protein p53 Homo sapiens