Title : HRD1 attenuates the high uptake of [18F]FDG in hepatocellular carcinoma PET imaging.

Pub. Date : 2021 May-Jun

PMID : 33725499






3 Functional Relationships(s)
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1 CONCLUSION: HRD1 inhibits the high uptake of [18F]FDG in HCC tumor cells by inducing degradation of GLUT1, which leads to decreased diagnostic efficiency of [18F]FDG PET imaging for HCC. Fluorodeoxyglucose F18 solute carrier family 2 member 1 Homo sapiens
2 CONCLUSION: HRD1 inhibits the high uptake of [18F]FDG in HCC tumor cells by inducing degradation of GLUT1, which leads to decreased diagnostic efficiency of [18F]FDG PET imaging for HCC. Fluorodeoxyglucose F18 solute carrier family 2 member 1 Homo sapiens
3 ADVANCES IN KNOWLEDGE: This study suggests that HRD1 inhibits the high uptake of [18F]FDG in HCC tumor by inducing degradation of GLUT1. Fluorodeoxyglucose F18 solute carrier family 2 member 1 Homo sapiens