Title : Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen.

Pub. Date : 2021 May 4

PMID : 33724805






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 MGL contains an extracellular calcium-dependent (C-type) carbohydrate recognition domain (CRD) that specifically binds terminal N-acetylgalactosamine glycan residues such as the Tn and sialyl-Tn antigens found on tumor cells, as well as other N- and O-glycans displayed on certain viruses and parasites. Carbohydrates C-type lectin domain containing 10A Homo sapiens