Title : Gluconeogenic enzyme PCK1 deficiency promotes CHK2 O-GlcNAcylation and hepatocellular carcinoma growth upon glucose deprivation.

Pub. Date : 2021 Apr 15

PMID : 33690219






1 Functional Relationships(s)
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1 Meanwhile, deletion of PCK1 also resulted in AMPK-GFAT1 axis inactivation promoting UDP-GlcNAc synthesis for elevated O-GlcNAcylation. o-glcnacylation glutamine fructose-6-phosphate transaminase 1 Mus musculus