Title : The study of antiviral drugs targeting SARS-CoV-2 nucleocapsid and spike proteins through large-scale compound repurposing.

Pub. Date : 2021 Mar

PMID : 33688584






1 Functional Relationships(s)
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Protein Name
Organism
1 Comparing to those under trial/temporarily used antivirus drugs (i.e., umifenovir, lopinavir), ceftriaxone, cefotaxime, and cefuroxime show higher binding affinities to the N-terminal domain of N protein (N-NTD), C-terminal domain of N protein (N-CTD), and receptor-binding domain of S protein (S-RBD). Cefotaxime surface glycoprotein Severe acute respiratory syndrome coronavirus 2