Pub. Date : 2021 Feb 20
PMID : 33685083
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Objective: To investigate the diagnosis method of Gilbert syndrome (GS) and the relationship between UGT1A1 gene polymorphism distribution with serum bilirubin. | Bilirubin | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |
| 2 | Among 110 cases with Gilbert syndrome combined with non-hemolytic diseases, pairwise comparisons showed that the total bilirubin levels of patients with UGT1A1*28/*28 mutations were significantly higher than UGT1A1*6/*6 and UGT1A1*1/*28 + *1/*6 mutation (P < 0.05). | Bilirubin | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |
| 3 | Among 110 cases with Gilbert syndrome combined with non-hemolytic diseases, pairwise comparisons showed that the total bilirubin levels of patients with UGT1A1*28/*28 mutations were significantly higher than UGT1A1*6/*6 and UGT1A1*1/*28 + *1/*6 mutation (P < 0.05). | Bilirubin | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |
| 4 | Among 110 cases with Gilbert syndrome combined with non-hemolytic diseases, pairwise comparisons showed that the total bilirubin levels of patients with UGT1A1*28/*28 mutations were significantly higher than UGT1A1*6/*6 and UGT1A1*1/*28 + *1/*6 mutation (P < 0.05). | Bilirubin | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |
| 5 | Additionally, with the increase of UGT1A1*28 distribution, the serum total bilirubin level had gradually increased (P = 0.028), but UGT1A1*6 was opposite (P = 0.021). | Bilirubin | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |