Pub. Date : 2020 Dec 29
PMID : 33680846
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tumour Necrosis Factor in Neuroplasticity, Neurogenesis and Alcohol Use Disorder. | Alcohols | tumor necrosis factor | Homo sapiens |
| 2 | Tumour necrosis factor (TNF) is a well characterised neuroimmune signal but its involvement in alcohol use disorder is unknown. | Alcohols | tumor necrosis factor | Homo sapiens |
| 3 | Tumour necrosis factor (TNF) is a well characterised neuroimmune signal but its involvement in alcohol use disorder is unknown. | Alcohols | tumor necrosis factor | Homo sapiens |
| 4 | Acute ethanol exposure reduces TNF release while chronic alcohol intake generally increases TNF levels. | Alcohols | tumor necrosis factor | Homo sapiens |
| 5 | Evidence suggests TNF potentiates excitatory transmission, promotes anxiety during alcohol withdrawal and is involved in drug use in rodents. | Alcohols | tumor necrosis factor | Homo sapiens |
| 6 | An association between craving for alcohol and TNF is apparent during withdrawal in humans. | Alcohols | tumor necrosis factor | Homo sapiens |
| 7 | Overall, defining TNF"s role in alcohol use disorder is complicated by poor understanding of its variable effects on synaptic transmission and neurogenesis. | Alcohols | tumor necrosis factor | Homo sapiens |
| 8 | Understanding the individual relevance of TNF in alcohol use disorder awaits a more comprehensive understanding of TNF"s effects within the brain. | Alcohols | tumor necrosis factor | Homo sapiens |