Title : Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on Disease Development/Progression, and Potential as Therapeutic Targets.

Pub. Date : 2021 Feb 22

PMID : 33671514






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 However, the most potent regulator of PFK-1 is fructose-2,6-bisphosphate (F-2,6-BP), the level of which is strongly associated with 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase activity (PFK-2/FBPase-2, PFKFB). fructose 2,6-diphosphate fructose-bisphosphatase 2 Homo sapiens
2 However, the most potent regulator of PFK-1 is fructose-2,6-bisphosphate (F-2,6-BP), the level of which is strongly associated with 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase activity (PFK-2/FBPase-2, PFKFB). fructose 2,6-diphosphate fructose-bisphosphatase 2 Homo sapiens
3 PFK-2/FBPase-2 is a bifunctional enzyme responsible for F-2,6-BP synthesis and degradation. fructose 2,6-diphosphate fructose-bisphosphatase 2 Homo sapiens