Title : Mesoscopic protein-rich clusters host the nucleation of mutant p53 amyloid fibrils.

Pub. Date : 2021 Mar 9

PMID : 33653952






1 Functional Relationships(s)
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1 We report that the p53 mutant R248Q (R, arginine; Q, glutamine) forms, both in cancer cells and in solutions, a condensate with unique properties, mesoscopic protein-rich clusters. Arginine tumor protein p53 Homo sapiens