Title : Introduction of Two Prolines and Removal of the Polybasic Cleavage Site Lead to Higher Efficacy of a Recombinant Spike-Based SARS-CoV-2 Vaccine in the Mouse Model.

Pub. Date : 2021 Mar 2

PMID : 33653892






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Exchange of K986 and V987 for prolines has been shown to stabilize the trimers of SARS-CoV-1 and the Middle East respiratory syndrome coronavirus spike proteins. Proline surface glycoprotein Severe acute respiratory syndrome coronavirus 2