Title : miR‑335 promotes ferroptosis by targeting ferritin heavy chain 1 in in vivo and in vitro models of Parkinson's disease.

Pub. Date : 2021 Apr

PMID : 33649797






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mechanistically, miR-335 enhanced ferroptosis through the degradation of FTH1 to increase iron release, lipid peroxidation and reactive oxygen species (ROS) accumulation, and to decrease mitochondrial membrane potential (MMP). Iron ferritin heavy chain 1 Homo sapiens