Pub. Date : 2021 Apr
PMID : 33641369
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In conclusion, interference with PPARgamma in vascular smooth muscle causes activation of the PGE2/EP3 signaling pathway in systemic and renal vasculature resulting in salt-induced impairment of vasodilation and salt-sensitive hypertension. | Dinoprostone | prostaglandin E receptor 3 (subtype EP3) | Mus musculus |
| 2 | PGE2/EP3 axis maybe a druggable target to prevent salt-sensitive hypertension in chronic conditions associated with decreased PPARgamma activity. | Dinoprostone | prostaglandin E receptor 3 (subtype EP3) | Mus musculus |