Title : BKM120 sensitizes BRCA-proficient triple negative breast cancer cells to olaparib through regulating FOXM1 and Exo1 expression.

Pub. Date : 2021 Feb 26

PMID : 33637776






2 Functional Relationships(s)
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1 BKM120 sensitizes BRCA-proficient triple negative breast cancer cells to olaparib through regulating FOXM1 and Exo1 expression. olaparib BRCA1 DNA repair associated Homo sapiens
2 We found that dual PI3K and PARP inhibition with BKM120 and olaparib significantly reduced the proliferation of BRCA-proficient TNBC cell lines MDA-MB-231 and MDA231-LM2. olaparib BRCA1 DNA repair associated Homo sapiens