Title : Four-pronged negative feedback of DSB machinery in meiotic DNA-break control in mice.

Pub. Date : 2021 Mar 18

PMID : 33619545






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Secondly, in their vicinity, DSBs trigger IHO1 depletion mainly by another DDR kinase, ATR. dsbs interactor of HORMAD1 1 Mus musculus
2 Thirdly, DSBs enable homologue synapsis, which promotes the depletion of IHO1 and pre-DSB recombinosomes from synapsed axes. dsbs interactor of HORMAD1 1 Mus musculus