Title : Exaggerated sympathetic and cardiovascular responses to dynamic mechanoreflex activation in rats with heart failure: Role of endoperoxide 4 and thromboxane A2 receptors.

Pub. Date : 2021 May

PMID : 33610008






1 Functional Relationships(s)
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1 In contrast, injection of the TxA2-R antagonist daltroban (80 mug) into the arterial supply of the hindlimb reduced the pressor response to dynamic hindlimb muscle stretch in HF-rEF (n = 11, peak MAP pre: 28 +- 4; post: 16 +- 2 mm Hg; P = 0.02) but not sham (n = 8, peak MAP pre: 17 +- 3; post: 16 +- 3; P = 0.84) rats. daltroban thromboxane A2 receptor Rattus norvegicus