Pub. Date : 2021 Apr 2
PMID : 33594365
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | For the theoretical triple mutant, we demonstrated through Alanine mutations, which help "unglue" key residue-residue interactions, that these three key stabilizing residues could cause the transition of Down to Up protomer states, where the Up protomer state allows binding of the prefusion Spike protein to hACE2 host cell receptors, whereas the Down state is believed inaccessible. | Alanine | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |