Pub. Date : 2021 Mar 31
PMID : 33593853
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Systemic administration of the COX2 inhibitor celecoxib suppressed both PGE2-induced heat hyperalgesia and Pdha1 phosphorylation in DRG of males but not females, suggesting that prostaglandin synthesis within the DRG mediates the phosphorylation of Pdha1 in response to hindpaw insult.SIGNIFICANCE STATEMENTThere has been extensive investigation of mitochondrial dysfunction as a causative factor in neuropathic pain disorders. | Celecoxib | cytochrome c oxidase II, mitochondrial | Mus musculus |