Title : A CD22-Shp1 phosphatase axis controls integrin β7 display and B cell function in mucosal immunity.

Pub. Date : 2021 Mar

PMID : 33589816






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 B cells with reduced Shp1 activity, lacking CD22 or expressing CD22 with mutated Shp1-binding or carbohydrate-binding domains displayed parallel reductions in surface alpha4beta7 and in homing to GALT. Carbohydrates CD22 molecule Homo sapiens