Title : Chronic nickel (II) exposure induces the stemness properties of cancer cells through repressing isocitrate dehydrogenase (IDH1).

Pub. Date : 2021 Apr 15

PMID : 33578097






2 Functional Relationships(s)
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1 Ni(II) also significantly decreased the protein expression of IDH1 and the synthesis rate of NAPDH, which competitively inhibited alpha-ketoglutarate (alpha-KG) generation. Ketoglutaric Acids isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens
2 Ni(II) also significantly decreased the protein expression of IDH1 and the synthesis rate of NAPDH, which competitively inhibited alpha-ketoglutarate (alpha-KG) generation. Ketoglutaric Acids isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens