Title : Cutting Edge of the Pathogenesis of Atopic Dermatitis: Sphingomyelin Deacylase, the Enzyme Involved in Its Ceramide Deficiency, Plays a Pivotal Role.

Pub. Date : 2021 Feb 5

PMID : 33562655






1 Functional Relationships(s)
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Protein Name
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1 Western blotting of samples treated with 2-mercaptoethanol revealed that whereas recombinant human aCDase was recognized by antibodies to the alpha-subunit at 56 and 13 kDa and the beta-subunit at 43 kDa, the purified SM deacylase was detectable only by the antibody to the beta-subunit at 43 kDa. Mercaptoethanol N-acylsphingosine amidohydrolase 1 Homo sapiens