Title : Calorimetric Analysis of the Interplay between Synthetic Tn Antigen-Presenting MUC1 Glycopeptides and Human Macrophage Galactose-Type Lectin.

Pub. Date : 2021 Feb 23

PMID : 33560106






1 Functional Relationships(s)
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1 Isothermal titration calorimetry (ITC) analysis of the binding of hMGL to this library of MUC1 glycopeptides revealed an enthalpy-driven process and an affinity enhancement of an order of magnitude with an increasing glycan count from 6-8 muM for monoglycosylated peptides to 0.6 muM for triglycosylated peptide. Glycopeptides C-type lectin domain containing 10A Homo sapiens