Title : Caffeine-Operated Synthetic Modules for Chemogenetic Control of Protein Activities by Life Style.

Pub. Date : 2021 Feb

PMID : 33552855






1 Functional Relationships(s)
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1 This CID tool, evolved from an anti-caffeine nanobody via cell-based high-throughput screening, permits caffeine-inducible gating of calcium channels, tumor killing via necroptosis, growth factors-independent activation of tyrosine receptor kinase signaling, and enhancement of nanobody-mediated antigen recognition for the severe acute respiratory distress coronavirus 2 (SARS-CoV-2) spike protein. Calcium surface glycoprotein Severe acute respiratory syndrome coronavirus 2