Title : The effects of metformin on autophagy.

Pub. Date : 2021 May

PMID : 33524789






1 Functional Relationships(s)
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1 First, many studies showed that metformin could induce autophagy via a number of signaling pathways, including AMPK-related signaling pathways (e.g. AMPK/mTOR, AMPK/CEBPD, MiTF/TFE, AMPK/ULK1, and AMPK/miR-221), Redd1/mTOR, STAT, SIRT, Na+/H+ exchangers, MAPK/ERK, PK2/PKR/AKT/ GSK3beta, and TRIB3. Metformin glycogen synthase kinase 3 alpha Homo sapiens