Title : Inhibition of organic cation transporter 3 activity by tyrosine kinase inhibitors.

Pub. Date : 2021 Oct

PMID : 33523504






1 Functional Relationships(s)
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1 Clinical concentrations of these three marketed TKIs, as well as those of pacritinib, were next predicted to inhibit in vivo OCT3 activity according to regulatory criteria. 11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene solute carrier family 22 member 3 Homo sapiens