Title : Nuclear translocation of the receptor tyrosine kinase c-MET reduces the treatment efficacies of olaparib and gemcitabine in pancreatic ductal adenocarcinoma cells.

Pub. Date : 2021

PMID : 33520371






2 Functional Relationships(s)
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1 Activation of the receptor tyrosine kinase c-MET positively correlates with poor prognosis for PDAC, and our previous study showed that nuclear c-MET can phosphorylate PARP1 at tyrosine 907 under ROS stimulation to promote DNA repair. Tyrosine MET proto-oncogene, receptor tyrosine kinase Homo sapiens
2 Activation of the receptor tyrosine kinase c-MET positively correlates with poor prognosis for PDAC, and our previous study showed that nuclear c-MET can phosphorylate PARP1 at tyrosine 907 under ROS stimulation to promote DNA repair. Tyrosine MET proto-oncogene, receptor tyrosine kinase Homo sapiens