Title : Exposure to aflatoxins and fumonisins and linear growth of children in rural Ethiopia: a longitudinal study.

Pub. Date : 2021 Aug

PMID : 33517942






3 Functional Relationships(s)
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1 OBJECTIVE: We hypothesize that exposure to aflatoxins and fumonisins, measured in serum, alters protein synthesis, reducing serum protein and insulin-like growth factor 1 (IGF-1), increasing inflammation and infection, leading to child linear growth failure. Aflatoxins insulin like growth factor 1 Homo sapiens
2 OBJECTIVE: We hypothesize that exposure to aflatoxins and fumonisins, measured in serum, alters protein synthesis, reducing serum protein and insulin-like growth factor 1 (IGF-1), increasing inflammation and infection, leading to child linear growth failure. Aflatoxins insulin like growth factor 1 Homo sapiens
3 In joint statistical tests, aflatoxin exposure was associated with serum biomarkers of inflammation (C-reactive protein, alpha-1-glycoprotein) and protein status (transthyretin, lysine, tryptophan), IGF-1, and linear growth (all p<0.01). Aflatoxins insulin like growth factor 1 Homo sapiens