Title : Mosaic IL6ST variant inducing constitutive GP130 cytokine receptor signaling as a cause of neonatal onset immunodeficiency with autoinflammation and dysmorphy.

Pub. Date : 2021 Apr 26

PMID : 33517393






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Interestingly, the STAT3 phosphorylation could be inhibited with ruxolitinib as well as tofacitinib, which are clinically approved JAK1 and JAK3 (to lesser extent JAK2 and JAK1) inhibitors, respectively. tofacitinib Janus kinase 3 Homo sapiens