Pub. Date : 2021 Mar 1
PMID : 33515544
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Resveratrol inhibits matrix metalloproteinase-1 and -3 expression by suppressing of p300/NFkappaB acetylation in TNF-alpha-treated human dermal fibroblasts. | Resveratrol | tumor necrosis factor | Homo sapiens |
| 2 | Resveratrol notably inhibited TNF-alpha-induced MMP-1 and MMP-3 upregulation and abrogated TNF-alpha-induced p65 acetylation, leading to the downregulation of MMP-1 and MMP-3 expression in TNF-alpha-treated cells. | Resveratrol | tumor necrosis factor | Homo sapiens |
| 3 | Resveratrol notably inhibited TNF-alpha-induced MMP-1 and MMP-3 upregulation and abrogated TNF-alpha-induced p65 acetylation, leading to the downregulation of MMP-1 and MMP-3 expression in TNF-alpha-treated cells. | Resveratrol | tumor necrosis factor | Homo sapiens |
| 4 | Resveratrol notably inhibited TNF-alpha-induced MMP-1 and MMP-3 upregulation and abrogated TNF-alpha-induced p65 acetylation, leading to the downregulation of MMP-1 and MMP-3 expression in TNF-alpha-treated cells. | Resveratrol | tumor necrosis factor | Homo sapiens |
| 5 | Our data indicate that TNF-alpha-induced p300-mediated p65 acetylation leads to the upregulation of MMP-1 and MMP-3 expression in dermal fibroblasts, whereas resveratrol reduces this TNF-alpha-induced upregulation by downregulating p300 expression. | Resveratrol | tumor necrosis factor | Homo sapiens |
| 6 | Our data indicate that TNF-alpha-induced p300-mediated p65 acetylation leads to the upregulation of MMP-1 and MMP-3 expression in dermal fibroblasts, whereas resveratrol reduces this TNF-alpha-induced upregulation by downregulating p300 expression. | Resveratrol | tumor necrosis factor | Homo sapiens |