Title : Mechanism of C-type inactivation in the hERG potassium channel.

Pub. Date : 2021 Jan

PMID : 33514547






1 Functional Relationships(s)
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1 Results suggest that C-type inactivation in hERG is associated with an asymmetrical constricted-like conformation of the selectivity filter, identifying F627 side-chain rotation and the hydrogen bond between Y616 and N629 as key determinants. Hydrogen ETS transcription factor ERG Homo sapiens